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KMID : 0861120050090010135
Korean Journal of Oriental Preventive Medicine
2005 Volume.9 No. 1 p.135 ~ p.141
Isolation of Antimicrobial Active Substances from Sophorae Radix
Kim Yun-Kyung

Han Wan-Soo
Jeong Seung-Il
Lee Ki-Nam
Kim Hyun-Ju
Lee Jeong-Ho
Abstract
Bioassay-directed fractionation of the dired roots of Sophorae Radix led to the isolation of Sophoraflavanone G. Their structures were elucidated using 1H-NMR, 13C-NMR, UV, IR and mass spectral ananlyses. These compounds exhibited a moderate antimicrobial activities against Streptococcus gordonii, Actinobacillus actinomycetemoomitans and Porphylomonas gingivalis.
KEYWORD
Sophorae Radix, Sophoraflavanone G, antibacterial activity
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