KMID : 0861120050090010135
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Korean Journal of Oriental Preventive Medicine 2005 Volume.9 No. 1 p.135 ~ p.141
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Isolation of Antimicrobial Active Substances from Sophorae Radix
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Kim Yun-Kyung
Han Wan-Soo Jeong Seung-Il Lee Ki-Nam Kim Hyun-Ju Lee Jeong-Ho
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Abstract
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Bioassay-directed fractionation of the dired roots of Sophorae Radix led to the isolation of Sophoraflavanone G. Their structures were elucidated using 1H-NMR, 13C-NMR, UV, IR and mass spectral ananlyses. These compounds exhibited a moderate antimicrobial activities against Streptococcus gordonii, Actinobacillus actinomycetemoomitans and Porphylomonas gingivalis.
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KEYWORD
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Sophorae Radix, Sophoraflavanone G, antibacterial activity
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